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Saturday, June 30, 2012

Android Grew A Whopping 500 Percent In India Last Year

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Video: President's 'Supreme' Victory

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Source: http://video.msnbc.msn.com/cnbc/48009750/

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FDA says Covidien device can get stuck in brain

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Gas Logs Vent Free - Beat The Summer Heat With Effective And ...

by Hansen Wholesale
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Gas Logs Vent Free More Details about Gas Logs Vent Free here.

With the rising temperature in June and July Ceiling fans plays an important role by circulating cool air in your room. Since electricity rates are rising the ceiling fan is one of the most common electronic equipment that allows you to reduce your electricity bills significantly. Besides that nowadays markets are full of attractive and beautiful Ceiling fans that help to make your furnishings of room look beautiful.

At present time the demand for ceiling fan has moved away from conventional fan with wood blades and complex glass shade. Now a smart and educated consumer finds ceiling fans that are well matched with the modern kitchen, stylish living room and even customary dining room and bedroom. During the purchase of a ceiling fan a consumer should consult the seller to find which type of style and size is advisable and effective for his requirement.

Selecting the appropriate size of ceiling fan for any desired location is essential for its performance and appearance. Since there is no clear or accurate medium to calculate right size of ceiling fan for particular area one can see number of calculators and charts online that provide different valuation. Ceiling fans are usually measured by their blade's length which must match with the size of the room where it has to be installed. The size of blades for home use purposes starts from 28 to 56 inches. The bulk of cooling of fan is experienced in the area under the blades of it. The more you move away from its blades, the cooling start getting reduced. One can notice that there is substantial decrease in the cooling when you move just 2 to 3 feet away from the tip of There is a significant drop off in airflow just outside of 2 feet from the angle of the blades of the fan. Eventually, the right size fan for a room is not only based on size of the room only, customer should also keep in account the outline of the area where it has to be installed.

Hunter Ceiling fans are regarded as the best fans that are offered in the market. From the past 100 years hunter is engaged in developing fans for both household purposes and commercial purposes. The main factors contributing to the success of hunter ceiling fans are that they are manufactured by talented workforce who is very proud of their work. That is why the similar tradition is gifted to the present generation of hunter fans.

Ceiling Fans with Lights refers to those fans which have decorative lights installed in centre, which not only makes the room glow with attractive lightening but also provide effective cooling and airflow to the room.

Thus Ceiling fans are not only affordable to purchase but are very effective in summers. Along with this they help in reducing the electricity bills considerably. Now days with introduction of Ceiling fans with lights they also enhance the d?cor of the area where they are placed.

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Keywords: Ceiling Fans, Hunter Ceiling Fans, Ceiling Fans With Lights, Gas Logs Vent Free

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Words Of Motivation: Beginning Self Improvement

?He who stops being better stops being good.?

Oliver Cromwell

Many aspects of the modern world seem simpler but at the same time life can be a lot more complicated overall. Certainly the widespread availability of information has the effect of making us more dissatisfied with the life we have and for this reason more and more people seek ways to make more of themselves.

There are certainly plenty of books and entries here on the Internet that give you advice and useful inspirational messages but most of it has little effect without a predetermined plan. All major projects need a blueprint to succeed and improving your life is no exception. We can call it a blueprint for success.

Getting started is always the most difficult part of any undertaking and a set plan will always help you on your way.

You could find outside help in finding your route to success. A mentor is ideal but can be hard to find. Perhaps the best way to find someone who can lead you is to look around for someone who is living the life you would like and ask them for their advice. Most people would be happy to help as this has to be one of the most sincere compliments you can pay anyone. Make sure however that they do indeed live the life you would like: many apparently successful business people, for example, have less than desirable private lives.

Another source of help would be a life coach. One of the signs of the popularity of self-improvement plans is the proliferation of life coaches. As with most professional advisors it is always best to find one recommended by someone you trust as there are good and bad examples around. There are many other services online that also seem to offer help but these too should be treated with caution ? particularly before parting with any money.

A good life coach or mentor is a great asset however. He or she will offer advice and words of motivation when they are needed and know which books would help fire you up. If you are looking for someone to help you in a specific area, such as self-employment, a good coach can also give you direction in terms of finances and marketing. Feedback is always useful as is the encouragement to keep going and a good mentor or coach will provide both. The journey to success is always harder when undertaken alone.

When starting a self-improvement programme it is always worth knowing the point from which you start. Be honest with yourself about your strengths and weaknesses. If you are lucky enough to have a spouse, coach or mentor this may be something you could discuss with them. This is particularly useful if that person already knows you well. It is important to focus on your strengths though as this sets you off on a positive footing.

Once you have identified your strengths and weaknesses, you might consider including some training of some kind to draw on your assets and improve areas where you may lack skills. Perhaps a local college offers a course that might help or a reputable online source might provide what you want (again, be careful if you are parting with money). In any case, learning will expand your mind and improve your self-worth.

Once you know where you stand you can safely plan where you want to be. Firstly you want to fully understand what are your dreams or ambitions. Once again you need to sit down and brainstorm what it is you want out of life. Why not think of your ideal day in a year?s time or perhaps in five or ten years? Let your imagination roll but make sure what you come up with is really what you want. Too many of us list dreams that will impress other people. What we are after is what will make you happy and fulfilled. Once you have your dreams clear, write them down.

Now we come to one of the vital elements of any self-development programme: goals. Many words have been written on the subject of goal-setting so a long discussion on the subject is not necessary here suffice to say that it is important to devise a list of steps, the achievement of which will bring you nearer to your dream life

Your ambitions are easier to achieve if you set goals that act as stepping-stones to the lifestyle you want to reach. It is important to remember that this will take time. A good, ambitious goal will take a while to reach and a series of smaller complimentary goals will help you stay motivated on the journey.

So you now have a list of goals leading you to the lifestyle you want. The key is to take action right away. A set of goals will get you excited for a short time but if you do nothing about them frustration will soon set in. Start immediately and your enthusiasm will grow with each goal you achieve.

The likelihood is that you will get addicted to improving your life so, once you achieve your major goals, you will want to set new ones and chase them to keep the momentum going. Indeed, Ralph Waldo Emerson describes this as ?the never-ending task of self-improvement?, so we should all spend our lives trying to be better.

Start your self-improvement now and life will always feel better.

Keith Braithwaite is a generally nosey and opinionated guy but his heart is in the right place. After nearly thirty years in the corporate world and twenty keenly observing direct selling, he is now following his interests in self-development, internet marketing and historical studies.

Join him on a journey to getting the most out of life using down to earth information (without the hype!)
http://www.InspirationMessages.com

Source: http://toddsblogs.com/selfimprovement/2012/06/28/words-of-motivation-beginning-self-improvement/

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Affirm Pain In Right Side Central Points | ArticlePDQ.com

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Source: http://articlepdq.com/health-fitness/affirm-pain-in-right-side-central-points/

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Study finds genes associated with hippocampal atrophy

Thursday, June 28, 2012

In a genome-wide association (GWA) study, researchers from Boston University Schools of Medicine (BUSM) and Public Health (BUSPH) have identified several genes which influence degeneration of the hippocampus, the part of the brain most associated with Alzheimer disease (AD). The study, which currently appears online as a Rapid Communication in the Annals of Neurology, demonstrates the efficacy of endophenotypes for broadening the understanding of the genetic basis of and pathways leading to AD.

AD is a progressive neurodegenerative disorder for which there are no prevention methods. Available drugs only marginally affect disease severity and progression, making AD effectively untreatable.

GWA studies using very large samples have increased the number of robust associations to 10 genes, including APOE. However, these genes account for no more than 35 percent of the inherited risk of AD and most of the genetic underpinning of the disorder remains unexplained. According to the researchers, magnetic resonance imaging (MRI) of the brain provides in vivo quantitative measures of neurodegenerative and cerebrovascular brain injury that may represent AD-related changes long before clinical symptoms appear. These measures are more powerful than comparisons of individuals with AD with cognitively healthy persons because they avoid misclassification of normal persons who will develop disease in the future.

BUSM researchers conducted a two-stage GWA study for quantitative measures of hippocampal volume (HV), total cerebral volume (TCV) and white matter hyperintensities (WMH). Brain MRI measures of HV, TCV and WMH were obtained from 981 Caucasian and 419 African-American AD cases and their cognitively normal siblings in the MIRAGE (Multi Institutional Research in Alzheimer's Genetic Epidemiology) Study. In addition, similar MRI measures were obtained from 168 AD cases, 336 individuals with mild cognitive impairment and 188 controls (all Caucasian) in the AD Neuroimaging Initiative (ADNI) Study. The MIRAGE Caucasian families and ADNI subjects were included in the first stage and the MIRAGE African American families were added in stage two. Results from the two Caucasians data sets were combined by meta-analysis.

In stage two, one genetic marker (i.e. single nucleotide polymorphism or SNP) from each of the gene regions that were most significantly associated with AD in the Caucasian data sets was evaluated in the African-American data set.

Novel genome-wide significant associations were observed for HV with SNPs in the APOE, F5/SELP, LHFP, and GCFC2 gene regions. All of these associations were supported by evidence in each data set.

"Our two-stage GWAS identified highly significant associations between a measure of degeneration in the brain region most strongly correlated with AD and several genes in both Caucasian and African American samples containing AD, cognitively impaired and cognitively healthy subjects. One of these associations was with the ?4 variant of APOE which is the most well-established genetic risk factor for AD.

Other associations were demonstrated with markers in F5/SELP, LHFP, and GCFC2, genes not previously implicated in this disease" explained senior author Lindsay Farrer, PhD, chief of biomedical genetics at BUSM. He also noted, "previous studies showed that blood level of P-selectin (the protein encoded by SELP) has been correlated with rate of cognitive decline in AD patients."

Farrer believes it is very likely that the number and specificity of these associations will increase in future studies using larger samples and focused on additional precise structural and functional MRI measures. "These findings will inform experiments designed to increase our understanding of disease-causing mechanism and may lead to new therapeutics targets," added Farrer.

###

Boston University Medical Center: http://www.bmc.org

Thanks to Boston University Medical Center for this article.

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Source: http://www.labspaces.net/121366/Study_finds_genes_associated_with_hippocampal_atrophy

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Friday, June 29, 2012

Hawaii bets right on SCOTUS health care ruling

Source: http://news.yahoo.com/hawaii-bets-scotus-health-care-ruling-124608283--finance.html

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Top court upholds healthcare law in Obama triumph

WASHINGTON (Reuters) - The U.S. Supreme Court upheld President Barack Obama's healthcare law on Thursday in an election-year triumph for him and fellow Democrats and a setback for Republican opponents of the most sweeping overhaul since the 1960s of the unwieldy U.S. healthcare system.

In a 5-4 ruling based on the power of Congress to impose taxes, the nation's highest court preserved the law's "individual mandate" requiring that most Americans obtain health insurance by 2014 or pay a tax. The justices also preserved, with some changes, a provision of the law expanding the Medicaid health insurance program for the poor.

Obama and Mitt Romney, the Republican challenger in the November 6 presidential election, immediately responded, with the president calling the ruling "a victory for people all over this country whose lives will be more secure because of this law and the Supreme Court's decision to uphold it."

"We will continue to implement this law and we'll work together to improve on it," said Obama, speaking somberly in the White House East Room, the same setting he used to announce the 2011 death of al Qaeda leader Osama bin Laden.

"What we won't do - what the country can't afford to do - is re-fight the political battles of two years ago or go back to the way things were. With today's announcement, it's time for us to move forward," Obama added.

Romney, who pushed through a similar healthcare overhaul at the state level in 2006 as governor of Massachusetts but opposed Obama's law, called on voters to help him defeat the president in order to repeal the law critics derisively call "Obamacare."

"If we're going get rid of 'Obamacare' we're going to have to replace President Obama. My mission is to make sure we do exactly that," Romney said on the roof of a building overlooking the U.S. Capitol.

Conservative Chief Justice John Roberts was joined by the court's four liberal members - Justices Ruth Bader Ginsburg, Stephen Breyer, Sonia Sotomayor and Elena Kagan - in upholding the law's pivotal "individual mandate" provision.

The four dissenters, all from the court's conservative wing, Justices Antonin Scalia, Anthony Kennedy, Clarence Thomas and Samuel Alito, would have struck down the entire law.

The healthcare law, known formally as the Patient Protection and Affordable Care Act, is the biggest overhaul of the $2.6 trillion healthcare system in about 50 years. It was signed by Obama in March 2010 and promptly put to the test in the courts by 26 of the 50 states and a trade group for small businesses.

The court's decision largely vindicates Obama and Democratic lawmakers in their attempt to fix a system that, while representing 18 percent of the economy, leaves 16 percent of Americans uninsured, a fact that sets the United States apart in the industrialized world.

The U.S. system, unlike other rich countries, is a patchwork of private insurance and restrictive government programs. The United States pays more for healthcare than any other country, but about 50 million of the roughly 310 million Americans still have no insurance at all.

The Obama law was meant to bring coverage to more than 30 million of the uninsured and slow soaring medical costs. Critics said it meddles too much in the lives of individuals and in the business of the states.

'CHARACTERIZED AS A TAX'

Opponents said the individual mandate was an overreach by the federal government and that Congress had exceeded its powers. The court was deeply divided on this issue, but the majority ruled that Congress's taxing authority allowed the mandate.

The law's "requirement that certain individuals pay a financial penalty for not obtaining health insurance may reasonably be characterized as a tax," Roberts wrote for the court's majority.

"Because the Constitution permits such a tax, it is not our role to forbid it, or to pass upon its wisdom or fairness," wrote Roberts.

In another part of the decision, the court said Congress went too far in a part of the law that requires states to expand the government's Medicaid health insurance program for the poor with the goal of covering more of the uninsured.

The court said this problem can be fixed by precluding the federal government from stripping states of existing Medicaid funds if they did not comply with the expansion, and that this did not require striking down other parts of the law.

DRAMATIC DAY AT COURT

The court began its session much as it always does. At 10 a.m. sharp, the marshal's familiar cry of "Oyez! Oyez! Oyez!" rang out as the nine justices entered through heavy scarlet drapes and took their seats at the tall mahogany bench.

The looks on their faces gave nothing away. As he took a seat, Chief Justice Roberts smiled slightly in the direction of the justices' guest seats, where his wife, Jane, was sitting.

As he and other justices read statements, it became obvious that Roberts, appointed by Republican President George W. Bush in 2005, had been the crucial vote upholding Obama's law.

Roberts showed he had taken control over a divided bench. He highlighted flaws in the administration's arguments and stressed the majority was not commenting on the wisdom of the law.

Rather, he said, if it could be upheld, the court must uphold it. He said it was not the job of the judiciary "to save" the nation from policy choices made by elected legislators.

Romney and the Republicans had hoped the Supreme Court would gut the law. Deprived of that outcome, they can now continue pressing the attack on Obama on the campaign trail, but their hopes for a rollback or repeal will hang on legislation, unlikely before the elections, and on the voting public, whose views are mixed.

"What the court did today was say that Obamacare does not violate the Constitution," Romney said. "What they did not do is say that Obamacare is good law, or good policy."

About 56 percent of Americans said they opposed the law in a Reuters/Ipsos poll released on Sunday. When asked about its individual provisions, however, most respondents said they strongly supported them, except for the individual mandate, which was opposed by 61 percent of those surveyed.

Most respondents in the survey favored banning insurers from denying coverage to people with pre-existing conditions; letting young adults stay on their parents' insurance plans until age 26; and making companies with more than 50 workers offer insurance to their employees. All are parts of the law.

So are the creation of state-based exchanges to offer health insurance; insurance premium assistance to poor people; and insurance tax credits for those just above the poverty line.

House of Representatives Speaker John Boehner, the top Republican in Congress, said, "Today's ruling underscores the urgency of repealing this harmful law in its entirety."

Eric Cantor, the No. 2 Republican in the House, said the House would vote on July 11 on legislation that would repeal the law. The Democratic-led Senate is certain to block any repeal legislation coming out of the Republican-controlled House.

Democrats hailed the court ruling as a posthumous victory for a longtime healthcare reform champion, Senator Ted Kennedy, who died in 2009. House Democratic leader Nancy Pelosi said she called his widow Vicki Kennedy to say: "Now, Teddy can rest.

Shares of hospital chains jumped, while large health insurer stocks fell after the ruling. Widening the pool of paying patients stands to benefit hospitals, which are often left to cover the high medical bills of the sick who have no coverage.

(Additional reporting by David Morgan, Donna Smith, Deborah Charles, Thomas Ferraro, Jeff Mason, Alister Bull and Laura MacInnis in Washington with Lewis Krauskopf in New York; Writing by Kevin Drawbaugh; Editing by Howard Goller and Will Dunham)

Source: http://news.yahoo.com/supreme-court-deliver-obama-healthcare-law-ruling-050529196.html

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Wake Forest Baptist study suggests Tasers don't cause cardiac complications

Public release date: 28-Jun-2012
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Contact: Bonnie Davis
bdavis@wakehealth.edu
336-399-8274
Wake Forest Baptist Medical Center

WINSTON-SALEM, N.C. June 28, 2012 Taser shots to the chest are no more dangerous than those delivered to other body locations, according to a new study by one of the country's leading experts on the devices.

William P. Bozeman, M.D., an associate professor of emergency medicine at Wake Forest Baptist Medical Center, and colleagues reviewed 1,201 cases of real-life Taser uses by law enforcement agencies but found none in which the devices could be linked to cardiac complications, even when the Taser probes landed on the upper chest area and may have delivered a shock across the heart.

Their findings are published online this month in the Journal of Emergency Medicine.

"While we know that the Taser is a very effective and remarkably safe weapon for law enforcement use, we also continue to have some concern about injuries that may be related to it," Bozeman said. "However, in this review, we found no cases where there was an apparent cardiac complication related to the Taser, even in the worst-case scenarios when the probes landed across the front of the chest and the heart may have been in the path of the electrical current produced by the device."

The team of researchers led by Bozeman reviewed cases of Taser use against criminal suspects by law enforcement officers from agencies across the country. Of the 1,201 cases reviewed, 178, or 22 percent, involved the device's probes landing on the suspect's chest and delivering an electrical charge that may have traveled across the heart area. The majority of the suspects in the reviewed cases were male (94 percent) and the mean age was 32. None of the suspects with Taser shots to the chest were found to have heart-related complications, and they did not have a higher injury rate than suspects with Taser shots elsewhere on the body.

Bozeman said it was important to conduct this research because concerns have been expressed that Taser activations across the front of the chest might be unsafe and should be avoided due to the possibility of probes landing near the heart. It also was important to look at real-life situations, he added, because criminal suspects are thought to be at a higher risk of complications than healthy volunteers because of the stress of the situation, the possible presence of drugs, underlying medical conditions and a variety of other factors.

"This analysis was done to assess whether medical data shows these concerns to be valid and whether law enforcement officers should change how the Taser is used in the field due to possible medical risks," Bozeman said. "The study results indicate that no adverse effects were seen that could be related to transcardiac conduction of Taser shocks."

Tasers are commonly used by law enforcement personnel worldwide as an intermediate-force option to subdue and apprehend potentially dangerous or combative suspects. Tasers function by delivering a series of very brief high-voltage, low-current electric pulses that result in pain, muscle contraction and inhibition of voluntary movement.

Bozeman has been conducting research into the use of Tasers by law enforcement personnel since 2004. In 2007 and 2009 he released results from the first large, independent study of injuries associated with Tasers, finding that they are relatively safe and pose minimal risk of injury. In that study, findings showed that 99.7 percent of those subjected to a Taser had no injuries or only mild ones, such as scrapes and bruises.

In a related study also released in 2009, Bozeman evaluated the immediate cardiac and cardiovascular effects on a group of volunteer police officers, finding that Taser exposure overall was safe and well tolerated. No adverse cardiac affects or rhythm changes were seen.

"This study adds to the accumulated medical evidence that Tasers are safe and effective and that their risks overall are extremely low," Bozeman said. "Although not risk free, Tasers have been associated with lower rates of injuries to suspects and officers than other traditional intermediate force options such as physical force, pepper spray, and handheld impact weapons."
###

This research was funded by the National Institute of Justice. Co-authors include James "Tripp" Winslow, M.D., of Wake Forest Baptist, and Eric Teacher, M.D., of Loma Linda University Medical Center in California.

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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.

Wake Forest Baptist study suggests Tasers don't cause cardiac complications Public release date: 28-Jun-2012
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Contact: Bonnie Davis
bdavis@wakehealth.edu
336-399-8274
Wake Forest Baptist Medical Center

WINSTON-SALEM, N.C. June 28, 2012 Taser shots to the chest are no more dangerous than those delivered to other body locations, according to a new study by one of the country's leading experts on the devices.

William P. Bozeman, M.D., an associate professor of emergency medicine at Wake Forest Baptist Medical Center, and colleagues reviewed 1,201 cases of real-life Taser uses by law enforcement agencies but found none in which the devices could be linked to cardiac complications, even when the Taser probes landed on the upper chest area and may have delivered a shock across the heart.

Their findings are published online this month in the Journal of Emergency Medicine.

"While we know that the Taser is a very effective and remarkably safe weapon for law enforcement use, we also continue to have some concern about injuries that may be related to it," Bozeman said. "However, in this review, we found no cases where there was an apparent cardiac complication related to the Taser, even in the worst-case scenarios when the probes landed across the front of the chest and the heart may have been in the path of the electrical current produced by the device."

The team of researchers led by Bozeman reviewed cases of Taser use against criminal suspects by law enforcement officers from agencies across the country. Of the 1,201 cases reviewed, 178, or 22 percent, involved the device's probes landing on the suspect's chest and delivering an electrical charge that may have traveled across the heart area. The majority of the suspects in the reviewed cases were male (94 percent) and the mean age was 32. None of the suspects with Taser shots to the chest were found to have heart-related complications, and they did not have a higher injury rate than suspects with Taser shots elsewhere on the body.

Bozeman said it was important to conduct this research because concerns have been expressed that Taser activations across the front of the chest might be unsafe and should be avoided due to the possibility of probes landing near the heart. It also was important to look at real-life situations, he added, because criminal suspects are thought to be at a higher risk of complications than healthy volunteers because of the stress of the situation, the possible presence of drugs, underlying medical conditions and a variety of other factors.

"This analysis was done to assess whether medical data shows these concerns to be valid and whether law enforcement officers should change how the Taser is used in the field due to possible medical risks," Bozeman said. "The study results indicate that no adverse effects were seen that could be related to transcardiac conduction of Taser shocks."

Tasers are commonly used by law enforcement personnel worldwide as an intermediate-force option to subdue and apprehend potentially dangerous or combative suspects. Tasers function by delivering a series of very brief high-voltage, low-current electric pulses that result in pain, muscle contraction and inhibition of voluntary movement.

Bozeman has been conducting research into the use of Tasers by law enforcement personnel since 2004. In 2007 and 2009 he released results from the first large, independent study of injuries associated with Tasers, finding that they are relatively safe and pose minimal risk of injury. In that study, findings showed that 99.7 percent of those subjected to a Taser had no injuries or only mild ones, such as scrapes and bruises.

In a related study also released in 2009, Bozeman evaluated the immediate cardiac and cardiovascular effects on a group of volunteer police officers, finding that Taser exposure overall was safe and well tolerated. No adverse cardiac affects or rhythm changes were seen.

"This study adds to the accumulated medical evidence that Tasers are safe and effective and that their risks overall are extremely low," Bozeman said. "Although not risk free, Tasers have been associated with lower rates of injuries to suspects and officers than other traditional intermediate force options such as physical force, pepper spray, and handheld impact weapons."
###

This research was funded by the National Institute of Justice. Co-authors include James "Tripp" Winslow, M.D., of Wake Forest Baptist, and Eric Teacher, M.D., of Loma Linda University Medical Center in California.

[ | E-mail | Share ]
?

AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.

Source: http://www.eurekalert.org/pub_releases/2012-06/wfbm-wfb062812.php
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Xbox Music said to rival Spotify and iTunes, Microsoft to make a mark in music

Xbox Music is coming to Windows 8 and Windows Phone 8, that much we know. We also know that the Zune brand is dead. But whether the new service will be a simple rebadge or an entirely new beast remains a mystery. Bloomberg has it on good authority, however, that that Xbox Music will more than just a new face. Microsoft is allegedly combining all the most successful elements of its competitors -- streaming, online storage, and offline syncing -- into a product that will put iTunes, Spotify and Google Play squarely in its crosshairs. The company is allegedly in talks with the record labels to secure the necessary rights for a monthly subscription service and a market for purchasing tracks. It will also take a page from Google Music and allow customers to upload their own collections. If Microsoft can pull off a such a comprehensive service others in the field better watch out -- few companies have the reach or budget of Redmond.

Xbox Music said to rival Spotify and iTunes, Microsoft to make a mark in music originally appeared on Engadget on Thu, 28 Jun 2012 16:57:00 EDT. Please see our terms for use of feeds.

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News organizations don't all get ruling right

NEW YORK (AP) ? A rush to quickly report the Supreme Court's decision on President Barack Obama's health care law on Thursday tripped up some news organizations that got it wrong and had to quickly correct themselves.

Both CNN and Fox News Channel initially reported incorrectly that the law's central provision, requiring virtually all Americans to have health insurance, had been struck down. In an apology, CNN said it "regrets that it didn't wait to report out the full and complete opinion regarding the mandate."

The Associated Press got it right, as did other news organizations and broadcast television outlets, generally. A minute after the AP flash alert at 10:07 a.m., The New York Times asked its readers for time, with Washington bureau chief David Leonhardt posting that reporters and editors were analyzing the decision.

"Once we are comfortable with its basic meaning, you can expect a torrent of coverage," he said. The Times next sent news via Twitter at 10:20.

It was a particularly embarrassing muff for CNN, which has suffered through one of its worst ratings quarters in several years, primarily due to a paucity of big news. The network eagerly awaited the Supreme Court's decision Thursday, running a "countdown clock" on its screen during the morning ticking down to 10 a.m.

Anchor Wolf Blitzer and reporter Kate Bolduan quickly reported that the health care law was struck down, based on a reading of Chief Justice John Roberts' decision that the mandate was not a valid exercise of congressional power under the commerce clause. Later in the reading, the justices found other reasons for upholding that portion of the law.

CNN's screen read: "Supreme Ct. Kills Individual Mandate."

"The court striking down that mandate is a dramatic blow to the president," said John King, CNN reporter.

The network also sent an email reporting that the mandate had been struck down and posted the news on Twitter.

By 10:13 a.m., some doubt had seeped in and the onscreen headline read: "Supreme Court Rules on Obama Law."

"Let's take a deep breath and see what the justices actually decided," Blitzer said. "It could be more complicated than we originally thought."

By 10:15, the network was reporting that the entire law had been upheld, and King called it "a huge, huge victory for President Obama."

Fox made the same initial mistake, with Bill Hemmer touting the "breaking news" that the individual mandate had been declared unconstitutional. Fox anchor Bret Baier tweeted the same news. Within two minutes, however, Megyn Kelly was citing the SCOTUSblog in casting doubt on that interpretation, even ordering producers to change an onscreen headline that read: "Supreme Court Finds Health Care Individual Mandate Unconstitutional."

"We're trying to do the best we can," Hemmer said.

Michael Clemente, Fox executive vice president of news and editorial, was unapologetic. "We gave our viewers the news as it happened ... Fox reported the facts, as they came in."

Several members of Congress tweeted incorrect information about the ruling, perhaps based on the initial misreading by cable networks.

Republican Rep. Darrell Issa of California called it a "big win for liberty and the Constitution. Rep. Tom Rooney (R, Fla.) said it was "great news for the American people, victory for constitution."

On CBS, Jan Crawford spoke on the air as she scanned the decision. "It appears, based on our quick summary, that the mandate, the individual mandate at the heart of this case may be in jeopardy under one provision of the constitution but they may have upheld the mandate under another provision."

ABC initially bobbled one detail ? calling the ruling 6-3 instead of 5-4 ? but correctly reported the outcome in a special report by Terry Moran. NBC's Pete Williams said that "the bottom line here is the Supreme Court has upheld the health care law."

___

CNN is a unit of Time Warner Inc.; Fox is owned by News Corp.; CBS is a division of CBS Corp.; ABC is owned by The Walt Disney Co.; NBC is controlled by Comcast Corp.

___

AP Television Writer Frazier Moore and AP Entertainment Writer Jake Coyle contributed to this report.

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Programmable DNA scissors found for bacterial immune system

ScienceDaily (June 28, 2012) ? Genetic engineers and genomics researchers should welcome the news from the Lawrence Berkeley National Laboratory (Berkeley Lab) where an international team of scientists has discovered a new and possibly more effective means of editing genomes. This discovery holds potentially big implications for advanced biofuels and therapeutic drugs, as genetically modified microorganisms, such as bacteria and fungi, are expected to play a key role in the green chemistry production of these and other valuable chemical products.

Jennifer Doudna, a biochemist with Berkeley Lab's Physical Biosciences Division and professor at the University of California (UC) Berkeley, helped lead the team that identified a double-RNA structure responsible for directing a bacterial protein to cleave foreign DNA at specific nucleotide sequences. Furthermore, the research team found that it is possible to program the protein with a single RNA to enable cleavage of essentially any DNA sequence.

"We've discovered the mechanism behind the RNA-guided cleavage of double-stranded DNA that is central to the bacterial acquired immunity system," says Doudna, who holds appointments with UC Berkeley's Department of Molecular and Cell Biology and Department of Chemistry, and is an investigator with the Howard Hughes Medical Institute (HHMI). "Our results could provide genetic engineers with a new and promising alternative to artificial enzymes for gene targeting and genome editing in bacteria and other cell types."

Doudna is one of two corresponding authors of a paper in the journal Science describing this work titled "A programmable dual RNA-guided DNA endonuclease in adaptive bacterial immunity." The second corresponding author is Emmanuelle Charpentier of the Laboratory for Molecular Infection Medicine at Sweden's Ume? University. Other co-authors of the paper were Martin Jinek, Krzysztof Chylinski, Ines Fonfara and Michael Hauer.

Bacterial and archaeon microbes face a never-ending onslaught from viruses and invading circles of nucleic acid known as plasmids. To survive, the microbes deploy an adaptive-type nucleic acid-based immune system that revolves around a genetic element known as CRISPR, which stands for Clustered Regularly Interspaced Short Palindromic Repeats. Through the combination of CRISPRs and associated endonucleases, called CRISPR-associated -- "Cas" -- proteins, bacteria and archaeons are able to utilize small customized crRNA molecules (for CRISPR-derived RNA) to target and destroy the DNA of invading viruses and plasmids.

There are three distinct types of CRISPR/Cas immunity systems. Doudna and her colleagues studied the Type II system which relies exclusively upon one family of endonucleases for the targeting and cleaving of foreign DNA, the Cas9 proteins.

"For the Type II CRISPR/Cas system, we found that crRNA connects via base-pairs with a trans-activating RNA (tracrRNA), to form a two-RNA structure," Doudna says. "These dual RNA molecules (tracrRNA:crRNA) direct Cas9 proteins to introduce double-stranded DNA breaks at specific sites targeted by the crRNA-guide sequence."

Doudna and her colleagues demonstrated that the dual tracrRNA:crRNA molecules can be engineered as a single RNA chimera for site-specific DNA cleavage, opening the door to RNA-programmable genome editing.

"Cas9 binds to the tracrRNA:crRNA complex which in turn directs it to a specific DNA sequence through base-pairing between the crRNA and the target DNA," Doudna says. "Microbes use this elegant mechanism to cleave and destroy viruses and plasmids, but for genome editing, the system could be used to introduce targeted DNA changes into the genome.

Doudna notes that the "beauty of CRISPR loci" is that they can be moved around on plasmids.

"It is well-established that CRISPR systems can be transplanted into heterologous bacterial strains," she says. "Also, there is evidence to suggest that CRISPR loci are horizontally transferred in nature."

Doudna and her colleagues are now in the process of gathering more details on how the RNA-guided cleavage reaction works and testing whether the system will work in eukaryotic organisms including fungi, worms, plants and human cells.

"Although we've not yet demonstrated genome editing, given the mechanism we describe it is now a very real possibility," Doudna says.

This work was funded primarily by the Howard Hughes Medical Institute, the Austrian Science Fund and the Swedish Research Council.

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Thursday, June 28, 2012

High court to deliver health care ruling Thursday

A view of the Supreme Court in Washington, Wednesday, June 27, 2012. Saving its biggest case for last, the Supreme Court is expected to announce its verdict Thursday on President Barack Obama's health care law. The outcome is likely to be a factor in the presidential campaign and help define John Roberts' legacy as chief justice. But the court's ruling almost certainly will not be the last word on America's tangled efforts to address health care woes. (AP Photo/Evan Vucci)

Dr. Nadya Hasham, a professor at Touro College medical school, examines Glenn Johnson at the Touro College Family Health Center on Wednesday, June 27, 2012 in Harlem, N.Y. The clinic provides affordable healthcare daily for one hundred individuals on average, according to a spokesperson, and accepts all walk-ins including the uninsured. Presidential candidates, governors of virtually every state, insurers with billions at stake, companies large and small and countless millions of Americans concerned about their own medical care and how they'll pay for it are awaiting a Supreme Court ruling expected Thursday on whether or not the Affordable Care Act passes the test of constitutionality. (AP Photo/Bebeto Matthews)

Nurse Tamika Edmonds, left, talks with patient LadiRoyale Davis before administering a shot at the William F. Ryan Community Health Center in New York, Wednesday, June 27, 2012. Presidential candidates, governors of virtually every state, insurers with billions at stake, companies large and small and countless millions of Americans concerned about their own medical care and how they'll pay for it are awaiting a Supreme Court ruling expected Thursday on whether or not the Affordable Care Act passes the test of constitutionality. (AP Photo/Seth Wenig)

Dr. Hamsakumari Ramasubramaniam, left, examines patient Fabian Vasquez at Camillus Health Concern, Wednesday, June 27, 2012, in Miami. Camillus is a private, non-profit organization that provides health care to the homeless and poor in Miami-Dade County. Presidential candidates, governors of virtually every state, insurers with billions at stake, companies large and small and countless millions of Americans concerned about their own medical care and how they'll pay for it are awaiting a Supreme Court ruling expected Thursday on whether or not the Affordable Care Act passes the test of constitutionality. (AP Photo/Lynne Sladky)

WASHINGTON (AP) ? They've known the outcome for three months. Now it's time for the nine Supreme Court justices to share it with the world.

Barring some incredibly strange twist, shortly after 10 o'clock in the morning Thursday, Chief Justice John Roberts is expected to reveal the high court's verdict on President Barack Obama's health care overhaul.

Between 400 and 500 people will crowd into the marble courtroom, the only witnesses to a historic moment that will not be broadcast live on television or radio. Some of those hoping for seats already were in line early Wednesday afternoon.

The court is not just passing judgment on a major expansion of the social safety net, designed to cover an additional 30 million Americans with health insurance. It is doing so on the president's signature domestic legislative achievement and in the heat of his closely fought campaign for re-election.

Four major issues await resolution, the most important of which is whether the law's centerpiece requirement that most people have health insurance or pay a penalty is constitutional. The justices also are weighing whether other parts or indeed the entire 2010 law should fall if they strike down the insurance requirement.

Apart from the insurance mandate, the court also is considering the validity of the health care law's significant expansion of Medicaid, the joint federal-state health care program for the poor.

One wrinkle could prevent the court from deciding the fate of the insurance requirement. A mid-19th century law prohibits challenges to taxes until they have been paid. The insurance requirement does not kick in until 2014 and people who pay the penalty won't do so until they file their 2014 income tax forms by April 15, 2015.

The court devoted more than six hours to arguments about these issues over three days in late March. The justices met March 30 to take a vote on the case and sort out who would take the lead in writing the opinions. In a case of this magnitude, the chief justice probably is writing the majority opinion, assuming he is in the majority.

The 26 states and the small business group challenging the law seemed to have the better of the courtroom arguments in March. Conservative justices peppered Solicitor General Donald Verrilli Jr. with hostile questions about both the insurance requirement and the Medicaid expansion.

But the lively arguments, the only time the justices discuss pending cases in public, are a relatively small part of a rather large record ? in this case, a mountain of more than 140 legal briefs.

Whatever the outcome, it seems certain to become part of the campaign between Obama and his Republican rival, Mitt Romney.

Obama could try to make the court itself, or more particularly its conservative majority, an issue if the insurance requirement or the whole law is struck down. For his part, Romney already has said he will try to take advantage of either outcome. If the law falls, Romney said it will show that "the first 3 1/2 years of this president's term will have been wasted on something that has not helped the American people." If the law is upheld, "we're going to have to have a president ? and I'm that one ? that's going to get rid of Obamacare. We're going to stop it on Day One," Romney said.

The case began almost as soon as Obama signed the law on March 23, 2010. Even before the day was out, Florida and 12 states filed the lawsuit that ended up at the Supreme Court. Another 13 states later joined in later.

The heart of the challenge was the claim that Congress could not force people to buy a product ? health insurance.

The administration advanced several arguments in defense of Congress' authority to require health insurance, including that it falls under the power to regulate interstate commerce.

The government also argued that the insurance requirement was necessary to make effective two other undoubtedly constitutional provisions: the requirements that insurers accept people regardless of existing health problems and limit what they charge older, sicker people.

The administration also said that even if the court rejected the first two arguments, the insurance requirement and penalty are constitutional as an exercise of Congress' power to enact taxes. The penalty assessed for not buying insurance functions like a tax, the government said.

Associated Press

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Is it stupid to refiance from a 15 year mortgage to 30 ... - Refinance

I coulds save 200month on my monthly payment but would have to start over again at 30 years from the current 15 years. I am really thinking about doing this because my spouse lost her job and needs to stay home to watch our young children instead of shelliung out childcare expenese. I have now and would go to 30 years at 5 is this stupid thank you so much.

Basic things about Is it stupid to refinance my existing mortage from 15 years to 30 years to reduce my monthy payment

Refinancing
Refinancing may refer to the replacement of an existing debt obligation with a debt obligation under. External links ? Streamlining your Mortgage ? Mortgage Refinancing.

Subordination agreement
Typically a subordination arises when there are two existing mortgages, a first mortgage and a second mortgage, and the mortgagor intends to refinance the first mortgage.

Cash out refinancing
? amount is above and beyond the cost of transaction, payoff of existing. total amount of equity that can be withdrawn with a cash-out refinance is dependent on the mortgage.

Reverse mortgage
A reverse mortgage is a form of equity release (or. be made to the house, and whether there are any existing. or heirs of the estate will have an option to refinance.

Subprime mortgage crisis
This enabled them to essentially bypass existing regulations regarding minimum. funding for Fannie Mae and Freddie Mac to purchase and more easily refinance mortgages.

5 is a great rate BUT 15years and your FREE Think of the Equity you will have and not to mention NO mortgage payment. Why not refinance your 15 years to that new ratge which is lower than 5 Its more than likely around or If it where me I would look at it and see how I could save week and keep the 15 year mortgage. Maybe I would watch 1 other child per week and that would make up the difference with money left over. REMEMBER it will cost you a couple of thousand dollars to close.

Financial Markets ECON 252 Real Estate is the biggest asset class and of great importance for both individuals and institutional investors. An array of economic and psychological factors impact real estate investment decisions and the public has changing ideas of real estate as a profitable investment. Peoples demand to buy a home by taking on longterm debt called a mortgage is often tied with the overall health of the economy and financial markets.

Commercial real estate held indirectly by the public through partnerships and real estate investment trusts REITs is vulnerable to similar speculative activity.

0000 Chapter 1. Introduction 0217 Chapter 2. The Development of Commercial Real Estate Assets from DPP to REIT 1734 Chapter 3.

The Math of Mortgages Fannie Mae and Freddie Mac 4150 Chapter 5. Understanding the Current Housing Boom Comparing Los Angeles and Milwaukee 5737 Chapter 6. Domestic and International Real Estate Booms Complete course materials are available at the Open Yale Courses website This course was recorded in Spring 2008.

I had a broker advise me on this but i dont know if it is such a good idea I have 14 years left on my mortage and if i refinance to 30 years i would save 215 a month off my payment. I really could use the money and i have NO credit card debt. Is this stupid to go from 14 to 30 years just to save 212 Its an attrative option but im not sure if i want to start over at 30 years again. I also plan on staying in this house you please so.

For the next 14 years it may not feel stupid to refinance into a 30 year but for 16 years after that it will Your 14 years from being debt free. My advice is to stay on the path and enjoy the riches in 14 years. Best of luck.

I saw someone else post something over this earlier i thought this would be I always see that snickers commercial and the guy throws the garbage cans. NO YESOVER and OVER again. I see the PSP commercial with the stalkerish guys who crave a PSP. Who could forget Built to last Duralast. Do you see any of these and name some others you see i have more but im just curious to see what annoying commericals you see in your area that repeat all the time as wellWQ If Kane and Taker are to retire around the same time would it be a good move for rateings in their sakes and respect to taker and kane by makeing one WWE and one World Heavyweight Championship.

The Brothers of Destruction owning the WWE. I think it could be a cool storyline if they break the Brands. Also if you used to watch raw they used to play Bod Man commericals all the guess what commerical they played on the Reunion on monday Bod and dear lord crude that IS one of the MOST annoying commericals ever.

HELL FREAKING NO You guys arent even close to the most annoying commercial Well there are 2One word BOFLEX That douchebag with the sunglasses and the gay tattoo on his back WTF And the guy has the balls to say I gave all of my clothes to all of my fat friends. What a douchebag Yeah my wife gives me that special wink now and then. AHOLE It used to be with that old guy in a rock band but the new one is WAY more annoyingAnd the 2nd one is Want to refinance your home That stupid old guy talking about refinancing your homes I understand a 30 second commercial but this dude has 2 freaking minutes EVERY SINGLE COMMERCIAL BRAKE GODThose are annoying.

Is it is a bad time to get into the mortgage business and also should I advise my friend to get out of the business he keeps telling me how much money he make but I keep reading bad things about it.

A career field is only as good as you want make it. If you are getting into the field to make money you will have a different attitude as oppose to a person that like the field. So your motivation for getting in the field will determine if you wake up in the morning and say damn this is a great day I can hardly wait to get to work and help people find mortgages to buy their dream home or refinance so they can send their daughter to college or damn another day at that stupid office I wonder why Mr Demings daughter want to go to college any way then why in the hell do that school teacher want to buy that house 2 miles from town damn I thing I will go back to sleep.

At one time I thought I wanted to be a school teacher hell they get the summer months off two weeks for Christmas and one week for Easter. I changed my mind when I found out about the unruly children the parents that think little Johnny and Jane are angels and then there is this stipend they called pay. Whatever business you get into you will need to know the good and bad as well as the educational and license requirements if any. So think over your reasons for getting into the mortgage business and it is always a good time to get into something you will enjoy and dont mind going to each morning that you wake up.

FIGHT ON.

Hey, W. and McCain: IT?S THE ECONOMY, STUPIDS!

Mind decide to refinance a fixed mortgage at 10 to a variable rate at 6 that later jumps to 15were.BumsAl On Sat 07 Jun 2008 170000 0700 Z ltbobbyHeres my a legislature that crams everything down your throat.Sorry but thats not what I want in my .

Mind decide to refinance a fixed mortgage at 10 to a variable rate at 6 that later jumps to 15 were.BumsAl On Sat 07 Jun 2008 170000 0700 Z ltbobbyHeres my a legislature that crams everything .

Bad News, accepted an offer on my house

Bad news I just got a decent offer on my house for sale in Florence. I came down in price 12 from my asking price. Later the appraisal of the property comes in 10000 below our agreed priceor the lender. Do you have to sell If not hold and sell for the price you want. Just refinance my house .

Or the lender. Do you have to sell If not hold and sell for the price you want. Just refinance my house of an area you dont want to beI know it sucks to loose money I lost close to 50K on the house my wife favorable .

OT: My friends?

Admitting youre wrong and that youllmake it better by refiing out. You go ahead and refinance. THAT is damned near the definition of stupid. Discountsomething before you even know what you are discountingOn Wed 04 Feb 2009 221758 GMT Wizard of Woodstock ltwizard?lets ponder this scenario. You .

THAT is damned near the definition of stupid. Discountsomething before you even know what you are discounting .

Home Buying: Why do realtors want me to apply to their mortgage company instead?

Why do realtors want me to apply to their mortgage company instead of my own chosen lenderdeal my client laying on the table I go in with my anesthesiologist and my nurse. These are who has been doing mortgages for a little bit into the operating room my team gets a little .

Deal my client laying on the table I go in with my anesthesiologist and my nurse. These are people Tilly who has been doing mortgages for a little bit into the operating room my team gets a little interests of the .

Banks

So FINALLY we have all the ducks in a row and should be signing documents tonight to refinancewith nicknames. It sounds stupid but it seriously makes my budgeting easier when I can have a car fundto the balance in my boyfriends other accounts and while I dont love them I dont hate them .

With nicknames. It sounds stupid but it seriously makes my budgeting easier when I can have a car fund to the balance in my boyfriends other accounts and while I dont love them I dont hate them too. I do ALL my bill ? .

Capital One GW Attempt

That my stupid 14 mistake may cause us to lose the refinance and thousands of dollars in savingsa bad month or I probably would have remembered. My stepson has mental health issues and hes beenwith them several times. If you get a no the first time just give it a day or two and call back. My .

With them several times. If you get a no the first time just give it a day or two and call back. My if they can put the loan in my husbands name only. I really appreciate all the help. Of all the times to make a stupid mistake? .

I do not write tests. Am I stupid?

Huge. If all I build are small apps am I stupid for not writing testsEdit To clarify whenIts not about being stupid or smart its about ensuring quality and maintainable code. If youup with happier answers to the above questions then stick with it.Youre not stupid for not doing .

Its not about being stupid or smart its about ensuring quality and maintainable code. If you up with happier answers to the above questions then stick with it.Youre not stupid for not doing to catch the bugs.The unexpected thing .

I get to keep my house!

Of more years lol.My lender calls me up and offers to restart my 5 year ARM and with a2 lower ltNaw I asked and I dont qualify for the Barry Bailout since mymortgage is not held by Fannie or Freddie. And even if it was myhouse is underwater way more than .

On ltNaw I asked and I dont qualify for the Barry Bailout since mymortgage is not held by Fannie or Freddie. And even if it was myhouse is underwater way more Naw I asked .

Apple iOS 6 drops Google Maps and adds everyday refinement

? Ill stick with android hell my old symbian phone did pretty much all the stuff that apple doesboi so my opinion will always be clouded but Apple havent really done anything innovative since in comparison. I ditched my standalone Sat Nav over 18 months ago because Googles turn by turn .

? Ill stick with android hell my old symbian phone did pretty much all the stuff that apple does boi so my opinion will always be clouded but Apple havent really done anything innovative since in comparison. I ditched my .

Wells fargo dealer services Complaints, Reviews ? RUDE Customer Service

Last year in April I bought my daughter a car. The finance company that approved the loanwas originally Wachovia. We had no issues up until they were bought out by Wells Fargo. My daughter lost herthat purchased a brand new Kia about 5 months ago my payments are a month and I make sure .

That purchased a brand new Kia about 5 months ago my payments are a month and I make sure its paid early because hell I need that car. Ive had my hardships but fact of the matter me had called my dad first. Im the .

History of the Republic of Singapore

Engage in her revised role of refining raw goods, as opposed to the comedy , satire and drama in the successful Singaporean film I Not Stupid . .

List of atheists (miscellaneous)

?It?s because they?re basically so stupid,? he asserted); it was Donner ?Hugh Falkus set about refining his techniques for Spey casting with .

Louisiana Tigers

These skull caps were mostly wore around camp as they was a stupid Educated under influences the most pious and refining, he was gentle, .

Wikipedia

File:Wiki feel stupid v2. first Kate last Hafner title Growing Wikipedia Refines Its ?Anyone Can Edit? Policy url http://www. .

List of United States Marine Corps acronyms and expressions

Ammunition in order to refine body position and other shooting fundamentals. gomer or GOMER ? antiquated slang for a stupid person, from .

Parsifal

And refine his Bayreuth production of Parsifal until his death in 1966. He thinks himself very stupid to have forgotten her. Kundry says .

What Where

Krapp: Just been listening to that stupid bastard I took myself for In 1987 Beckett worked with Stan Gontarski and John Reilly to refine .

Community of Wikipedia

That is ?for the most part stupid and boring?, and asks, r 1&scp 8&sq wikipedia&st cse ?Growing Wikipedia Refines Its ?Anyone Can Edit? .

Charles Sanders Peirce

refining the use of pendulum s to determine small local variations skillful hypotheses will ascertain what 200,000 stupid ones might fail to do. .

Andrew Robinson (Neighbours)

I have had to refine it so the other cast members and audience can the single most stupid thing he?s done so far, and that?s saying something.? .

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