Wednesday, July 10, 2013

Laser-powered atomic clock fuels temporal pedants' ire

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If you thought that your regular atomic clock, which loses a second once every few years, is adequate for your needs, then Dr. Jerome Lodewyck wants a word. His team at the Paris Observatory claims to have invented an atomic clock which only loses a second every three centuries. Rather than measuring the oscillations of caesium atoms, the "Optical Lattice Clock" uses a laser to excite strontium atoms which vibrate much faster and are, therefore, more accurate. Of course, it's a cruel irony that just as soon as someone's plonked down $78,000 on a Hoptroff No. 10, a rogue gang of scientists find a way to make it obsolete.

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Via: BBC News

Source: Nature

Source: http://feeds.engadget.com/~r/weblogsinc/engadget/~3/FHyBVk_Vnso/

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GOP redistricting skills may hurt immigration push

FILE - In this April 16, 2013 file photo, House Majority Whip Kevin McCarthy of Calif. speaks during news conference on Capitol Hill in Washington. Republicans? knack for congressional redistricting helps them control the U.S. House. But it may be working against them on immigration and other issues important to presidential elections. House Republicans generally represent far fewer Hispanics than do Democrats, thanks in part to a politicized redistricting process that packs minorities into Democratic-leaning districts. That leaves GOP representatives with lots of white conservatives, many of whom oppose ?amnesty? for immigrants living here illegally, lawmakers say. (AP Photo/Jacquelyn Martin, File)

FILE - In this April 16, 2013 file photo, House Majority Whip Kevin McCarthy of Calif. speaks during news conference on Capitol Hill in Washington. Republicans? knack for congressional redistricting helps them control the U.S. House. But it may be working against them on immigration and other issues important to presidential elections. House Republicans generally represent far fewer Hispanics than do Democrats, thanks in part to a politicized redistricting process that packs minorities into Democratic-leaning districts. That leaves GOP representatives with lots of white conservatives, many of whom oppose ?amnesty? for immigrants living here illegally, lawmakers say. (AP Photo/Jacquelyn Martin, File)

(AP) ? Republicans' knack for congressional redistricting helps them control the U.S. House, but it may be working against them on immigration changes that national GOP leaders see as critical to the next presidential election.

House Republicans generally represent far fewer Hispanics than Democrats do. And that leaves many GOP members representing white conservatives, many of whom oppose a path to citizenship for immigrants living here illegally.

The combination poses a high hurdle for passage of a comprehensive immigration overhaul in the Republican-controlled House. The Senate has passed such a measure, which includes an eventual pathway to citizenship, accompanied by greater border security.

A GOP-sanctioned study of Mitt Romney's November defeat concluded that the party must embrace immigration reform to stem its huge losses among Hispanic voters, a fast-growing group. But dozens of House Republicans have a far greater fear: inviting GOP primary challengers from the right by failing to appease their most conservative constituents.

"House members would clearly be taking a risk in supporting any kind of immigration reform that includes a path to citizenship," said Emory University political scientist Alan Abramowitz. "There's clearly a tension here between what would be in the interest of the Republican Party" ? particularly in presidential races ? "and what would be in the interest of individual Republicans, especially in the House."

Both Republicans and Democrats in many states have refined the art of congressional gerrymandering, in which they draw House districts to be as strongly conservative or liberal as possible. Adding to the partisan divide are decisions by millions of Americans to live among politically like-minded people. And partisan-tinged radio and TV programs shower lawmakers and constituents with ideological reinforcement.

While Democrats gerrymander districts too, GOP control of many state governments after the 2010 Census let Republicans draw an unusual number of House districts to their liking. Now, from a presidential election viewpoint, Republicans may be choking on their success.

Rep. Kevin McCarthy of California, the House's third-ranking Republican leader, notes the partisan disparity in Hispanic representation. The average Hispanic proportion of a Democrat's House district is 23 percent, he tells colleagues, while it's 11 percent for Republicans. Of the House's 234 Republicans, 106 have districts in which Hispanics make up less than 6 percent of all residents.

With conservative and liberal activists dominating Republican and Democratic primaries, respectively, lawmakers are being chosen by "very unrepresentative voters," said Mickey Edwards, a former Republican congressman from Oklahoma. If you're a lawmaker from a solidly partisan district, Edwards said, "you don't worry about the general election. You make sure you win the primary."

For many Republicans, he said, that means constantly veering right. On issues such as immigration, Edwards said, some Americans say, "'What's wrong with these people, they're irrational.'" In fact, he said, "the opposite is true. They are very rational."

At a meeting with constituents last week, GOP Rep. Justin Amash ? whose Michigan district is about 7 percent Hispanic ? heard sharp criticisms of the Senate immigration bill.

"Compromise is the crucifixion of conscience," said Terri Rogers, 66, of Cedar Springs, Mich.

She dismissed Amash's argument that the millions of immigrants living here illegally can't be rounded up and deported. "You break the law, you go to jail ? or at least go home," Rogers said. She suggested the U.S. military handle the task.

Even in districts with more Hispanics than Amash has, they "generally aren't the voters that Republicans are counting on" to win the all-important party primaries, Abramowitz said. That's because most Hispanics lean Democratic, as President Barack Obama proved by winning 71 percent of their vote last fall.

John Feehery, a GOP strategist and former House aide, said he once thought anti-immigrant sentiment would run lower in areas with relatively few Hispanics. Instead, he said, it seems "the fewer Hispanics you have in your district, the more you're against immigration reform."

House members will vote the interests of their districts and their primary-election needs, Feehery said. "Members are worried about a tea party challenge," he said. "They're not going to worry about presidential politics."

Rep. Tom Cole of Oklahoma is close to House Republican leaders, and he agrees that immigration reform would help the party's presidential prospects. However, he said, "people feel so strongly about this issue that it's extremely difficult to fashion a bill that will get a majority of the Republicans and a Democratic Senate and a Democratic president."

When House Republicans see their re-election efforts conflicting with the party's presidential goals, Cole said, "their own race almost certainly is going to come first, every time."

___

Associated Press writer David Eggert in Michigan contributed to this report. Follow Charles Babington on Twitter: https://twitter.com/cbabington.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/89ae8247abe8493fae24405546e9a1aa/Article_2013-07-09-GOP%20Districts-Immigration/id-16fe90c59dd04961a03a4b81fa4b8cfe

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AstraZeneca signs up first Cambridge partners in cancer research

LONDON (Reuters) ? British pharmaceutical company AstraZeneca has agreed its first research partnerships in Cambridge for cancer treatments ahead of its relocation to the university city by 2016. The firm said it would work on three oncology proje?

Full Story Via Yahoo! Health News

Source: http://scooprocket.com/health/2013/07/09/astrazeneca-signs-up-first-cambridge-partners-in-cancer-research/

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Statins Have Few Side Effects, But Should More People Be Taking Them?

Statins lower cholesterol, reduce inflammation and may be responsible for saving thousands of lives. Should everyone be taking the wonder drug?

In the latest study investigating the side effects o statins, researchers report in the journal Circulation: Cardiovascular Quality and Outcomes, that the best-selling drugs are relatively safe. And as evidence builds that statins can lower inflammation, the process responsible for many chronic illnesses, from Alzheimer?s to cancer and heart disease, some experts are suggesting that more people should be taking advantage of the prescription medication to slow down aging.

The results of the Circulation paper may bolster that idea. The study?s lead author, Huseyin Naci, a research fellow at Harvard Medical School in the department of population medicine, pooled 135 studies involving 250,000 participants and all seven of the currently available statin medications and analyzed the risk of side effects. The studies were those that drug makers submitted to the Food and Drug Administration to demonstrate the safety of their medications for approval. Naci and his colleagues found a 9% increased risk of diabetes among those who used statins compared to those who were assigned placebo pills. The rates of other side effects, including muscle pain, cancer, and changes in liver enzymes were not statistically significant.

MORE: Who Should Take Statins? The Debate Continues

Such a relatively safe side effect profile could reignite the debate over whether more people should be taking statins ? or, as some researchers in the UK and US have suggested, whether everyone over age 40 or 50 should be on the medication.? Dr. David Agus, professor of medicine at the University of Southern California Keck School of Medicine, recommends that everyone over 40 should discuss statins with their doctor, even if they haven?t had heart problems or are at increased risk for heart disease or diabetes. He says that inflammation is driving a number of aging-related conditions, both in the body and brain, and since studies have shown that statins are a powerful way to dampen the inflammatory response, more people might be living longer if they take advantage of statins. Rory Collins, an epidemiologist at Oxford University, caused an uproar last year when he addressed the European Society of Cardiology with a talk entitled, ?The Case for Statins In a Wider Population,? and argued that more people should be availing themselves of the medications, just as they do aspirin.

Not everyone agrees with that view, however, despite the favorable side effect profile of the drugs. ?It?s a wonderful medication, but we shouldn?t be putting statins in the water supply,? says Dr. Steven Nissen, chair of cardiovascular medicine at Cleveland Clinic. Naci also says that although his analysis showed that the drugs were relatively safe, ?we don?t know the long term effects of statins. If we give it everyone, then after ten or 15 years we don?t know what the slight increased risk of diabetes will amount to.? Statin drugs have been linked to an increased risk of muscle weakness as well, which was severe enough for one medication to be pulled off the market.

MORE: Should You Take Statins? Study Says Heart Benefits Outweigh Diabetes Risk

There?s no argument that patients who have already had a heart attack or heart disease can lower their risk of further heart problems by taking a statin. What?s less clear is whether people who are otherwise healthy could lower their risk enough to justify their exposure to the side effects of the medications. And to answer that question, scientists are turning to statins? ability to reduce inflammation.

Currently, national guidelines recommend that patients start on statins based on their cholesterol levels. But doctors are investigating whether people with low cholesterol levels but high inflammation levels could benefit from statins. A recent trial showed that these patients, who under existing guidelines would not be advised to take statins, could lower their risk of a heart attack or stroke by 50% if they were taking the drug. To confirm the association between inflammation and a lower risk of heart events, Dr. Paul Ridker, director of the center for cardiovascular disease prevention at the Brigham and Women?s Hospital and a pioneer in understanding inflammation?s role in heart disease, is spearheading two trials involving heart patients on statins. Half will be randomly assigned to take another anti-inflammatory agent on top of their statin, while half will be assigned a placebo; if the group taking the anti-inflammatory agent ends up with a lower rate of heart problems, then that would support the idea that inflammation indeed plays a critical role in heart disease, and that controlling it with a statin might save more lives.

MORE:?Statins: Evidence of Broader Benefits

?We already know that the risk associated with elevated inflammation is as large as the elevated risk patients have from having either high cholesterol or high blood pressure,? he says. ?The question is, just as lowering blood pressure reduces risk, can we generate evidence that reducing inflammation reduces the risk of heart disease.?

Even if the results of those trials show that lowering inflammation also lowers risk of heart problems, that won?t mean that everyone should be taking a statin. ?One has to be cautious about for whom we recommend [statin] therapies,? says Dr. Sidney Smith, professor of medicine at the University of North Carolina Chapel Hill and past president of the American Heart Association. ?We are going to have to do a better job of identifying patients at risk who might benefit from medical therapies to reduce their risk of heart disease at a dosage that minimizes the side effects.?

That?s especially true for the youngest patients ? children ? who are increasingly being tested for high cholesterol levels and even prescribed the medications that most associate with middle-age. In 2008, I wrote about the American Academy of Pediatrics? recommendation to broaden cholesterol testing to include toddlers as young as two and to consider prescribing statins for youngsters with a history of abnormally high cholesterol levels:

While the guidelines target kids with a genetic risk of abnormally high cholesterol, called hyperlipidemia, they could lower the bar for prescriptions?not just for these children but for any overweight youngster whose cholesterol is not in check. Within hours of the AAP announcement on July 7, parents took to the blogs, expressing shock and unease over the aggressiveness of the guidelines. Statins are not without risks; in adults, in rare cases, they can cause muscle weakness and kidney problems, and there are limited data on how statins affect children.

The Academy defended its position, maintaining that the benefits of addressing cholesterol in children, which can lower their risk of diabetes and heart disease, outweighed the risks of the medications. Making such risk-benefit calculations about statin use for non-heart patients continues to be a work-in-progress, says Smith, but new national guidelines may help doctors to make those calculations in the coming year. ?We still need to carefully define the groups that will benefit,? he says. ?I think we will do a better job of that based on studies like this and others that have come out in the past few years. Hopefully within the next year we will be able to pull some things together that will allow us to move forward and do good things for our patients.?

Source: http://news.yahoo.com/statins-few-side-effects-more-people-taking-them-094544365.html

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Washington Beat: Partisan Gridlock Could Halt Congress' Summer Assignments

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Tuesday, July 9, 2013

Pilot in SF crash had little experience with 777s

Parents of Wang Linjia, center, are comforted by parents of some other students who were on the Asiana Airlines Flight 214 when it crashed at San Francisco International Airport, while they gather and wait for news of their children at Jiangshan Middle School in Jiangshan city, in eastern China's Zhejiang province, Sunday July 7, 2013. Chinese state media have identified the two people who died in the plane crash at San Francisco International Airport on Saturday as Ye Mengyuan and Wang Linjia, 16-year-old students at Jiangshan Middle School in China's eastern Zhejiang province. (AP Photo) CHINA OUT

Parents of Wang Linjia, center, are comforted by parents of some other students who were on the Asiana Airlines Flight 214 when it crashed at San Francisco International Airport, while they gather and wait for news of their children at Jiangshan Middle School in Jiangshan city, in eastern China's Zhejiang province, Sunday July 7, 2013. Chinese state media have identified the two people who died in the plane crash at San Francisco International Airport on Saturday as Ye Mengyuan and Wang Linjia, 16-year-old students at Jiangshan Middle School in China's eastern Zhejiang province. (AP Photo) CHINA OUT

This frame grab from video provided by KTVU shows the scene after an Asiana Airlines flight crashed while landing at San Francisco Airport on Saturday, July 6, 2013, in San Francisco. (AP Photo/KTVU) MANDATORY CREDIT

A fire truck sprays water on Asiana Flight 214 after it crashed at San Francisco International Airport on Saturday, July 6, 2013, in San Francisco. (AP Photo/Noah Berger)

This photo provided by Antonette Edwards shows what a federal aviation official says was an Asiana Airlines flight crashing while landing at San Francisco airport on Saturday, July 6, 2013. It was not immediately known whether there were any injuries. (AP Photo/Antonette Edwards )

This photo provided by Wei Yeh shows what a federal aviation official says was an Asiana Airlines flight crashing while landing at San Francisco airport on Saturday, July 6, 2013. It was not immediately known whether there were any injuries. (AP Photo/Wei Yeh)

(AP) ? The pilot at the controls of an Asiana plane that crashed landed was guiding a Boeing 777 into the San Francisco airport for the first time, and tried but failed to abort the landing after coming in too slow to set down safely, aviation and airline officials said Sunday.

It was unclear if the pilot's inexperience with the aircraft and airport played a role in Saturday's crash. Officials were investigating whether the airport or plane's equipment could have also malfunctioned.

Also Sunday, San Mateo County Coroner Robert Foucrault said he was investigating whether t one of the two teenage passengers killed Saturday actually survived the crash but was run over by a rescue vehicle rushing to aid victims fleeing the burning aircraft. Remarkably, 305 of 307 passengers survived the crash and more than a third didn't even require hospitalization. Only a small number were critically injured.

Deborah Hersman, head of the National Transportation Safety Board, said the slow speed of Flight 214 in the final approach triggered a warning that the jetliner could stall, and an effort was made to abort the landing but the plane crashed barely a second later.

At a news conference, Hersman disclosed the aircraft was traveling at speeds well below the target landing speed of 137 knots per hour, or 157 mph.

"We're not talking about a few knots," she said.

Hersman described the frantic final seconds of the flight as the pilots struggled to avoid crashing.

Seven seconds before the crash, pilots recognized the need to increase speed, she said, basing her comments on an evaluation of the cockpit voice and flight data recorders that contain hundreds of different types of information on what happened to the plane. Three seconds later, the aircraft's stick shaker ? a piece of safety equipment that warns pilots of an impending stall ? went off. The normal response to a stall warning is to boost speed and Hersman said the throttles were fired and the engines appeared to respond normally.

At 1.5 seconds before impact, there was a call from the crew to abort the landing.

The details confirmed what survivors and other witnesses said they saw: an aircraft that seemed to be flying too slowly just before its tail apparently clipped a seawall at the end of the runway and the nose slammed down.

Pilots normally try to land at the target speed, in this case 137 knots, plus an additional five more knots, said Bob Coffman, an American Airlines captain who has flown 777s. He said the briefing raises an important question: "Why was the plane going so slow?"

The plane's Pratt & Whitney engines were on idle and the pilots were flying under visual flight rules, Hersman said. Under visual flight procedures in the Boeing 777, a wide-body jet, the autopilot would typically have been turned off while the automatic throttle, which regulates speed, would been on until the plane had descended to 500 feet in altitude, Coffman said. At that point, pilots would normally check their airspeed before switching off the autothrottle to continue a "hand fly" approach, he said.

There was no indication in the discussions between the pilots and the air traffic controllers that there were problems with the aircraft.

The airline said Monday in Seoul that the pilot at the controls had little experience flying that type of plane and was landing one for the first time at that airport.

Asiana spokeswoman Lee Hyomin said that Lee Gang-guk, who was at the controls, had nearly 10,000 hours flying other planes but only 43 in the 777, a plane she said he still was getting used to flying. Another pilot on the flight, Lee Jeong-min, had about 12,390 hours of flying experience, including 3,220 hours on the 777, according to the Ministry of Land, Infrastructure and Transport in South Korea. Lee was the deputy pilot, tasked with helping Lee Gang-guk get accustomed to the 777, according to Asiana Airlines.

Asiana spokeswoman Lee Hyomin said that Lee Gang-guk was trying to get used to the 777 during Saturday's crash landing. She says the pilot had nearly 10,000 hours flying other planes but had only 43 hours on the 777.

Among the questions investigators are trying to answer was what, if any, role the deactivation of a ground-based landing guidance system due to airport construction played in the crash. Such systems help pilots land, especially at airports like San Francisco where fog can make landing challenging. The conditions Saturday were nearly perfect, with sunny skies and light winds.

The flight originated in Shanghai, China, stopped over in Seoul, South Korea, before making the nearly 11-hour trip to San Francisco. The South Korea-based airline said four South Korean pilots were on board, three of whom were described as "skilled."

Among the travelers were citizens of China, South Korean, the United States, Canada, India, Japan, Vietnam and France. There were at least 70 Chinese students and teachers heading to summer camps, according to Chinese authorities.

Fei Xiong, a Chinese passenger , was traveling to California so she could take her 8-year-old son to Disneyland. The pair was sitting in the back half of the plane. Xiong said her son sensed something was wrong.

"My son told me: 'The plane will fall down, it's too close to the sea,'" she said. "I told him: 'Baby, it's OK, we'll be fine.'"

When the plane hit the ground, oxygen masks dropped down, said Xu Da, a product manager at an Internet company in Hangzhou, China, who was sitting with his wife and teenage son near the back of the plane. When he stood up, he said he could see sparking ? perhaps from exposed electrical wires.

He turned and could see the tail where the galley was torn away, leaving a gaping hole through which they could see the runway. Once on the tarmac, they watched the plane catch fire, and firefighters hose it down.

"I just feel lucky," said Xu, whose family suffered some cuts and have neck and back pain.

In the chaotic moments after the landing, when baggage was tumbling from the overhead bins onto passengers and people all around her were screaming, Wen Zhang grabbed her 4-year-old son, who hit the seat in front of him and broke his leg.

Spotting a hole at the back of the jumbo jet where the bathroom had been, she carried her boy to safety.

"I had no time to be scared," she said.

Authorities immediately closed the airport and rescuers rushed to the scene. A United Airlines pilot radioed the control tower, saying: "We see people ... that need immediate attention. They are alive and walking around."

"Think you said people are just walking outside the airplane right now?" the controller replied.

"Yes," answered the pilot of United Flight 885. "Some people, it looks like, are struggling."

At the crash scene, police officers knives up to crew members inside the burning wreckage so they could cut away passengers' seat belts. Passengers jumped down emergency slides, escaping from billowing smoke that rose high above the bay. Some passengers who escaped doused themselves with water from the bay, presumably to cool burns, authorities said.

By the time the flames were out, much of the top of the fuselage had burned away. The tail section was gone, with pieces of it scattered across the beginning of the runway.

Foucrault, the coroner, said senior San Francisco Fire Department officials notified him and his staff at the crash site on Saturday that one of the 16-year-olds who was kilkled may have been struck on the runaway. Foucrault said an autopsy he expects to be completed by Monday will involve determining whether the girl's death was caused by injuries suffered in the crash or "a secondary incident."

He said he did not get a close enough look at the victims on Saturday to know whether they had external injuries.

Foucrault said one of the bodies was found on the tarmac near where the plane's tail broke off when it slammed into the runway. The other was found on the left side of the plane about 30 feet away from where the jetliner came to rest after it skidded down the runway.

___

Lowy reported from Washington, D.C. Associated Press writers Terry Collins, Terry Chea and Sudhin Thanawala in San Francisco, David Koenig in Dallas and Louise Watt in Beijing contributed to this report.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/cae69a7523db45408eeb2b3a98c0c9c5/Article_2013-07-08-San%20Francisco%20Airliner%20Crash/id-833793a3e4544224aa7334b6e40fe315

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Fire department adds 15 jobs

After five years without a new class of city firefighters, city officials and the Fort Wayne Fire Department Monday announced a $1.2 million plan to get more firefighters beginning next year.

The department will add 15 firefighters using taxpayer dollars collected through a local option income tax approved by the City Council, officials said.

?After five years of having to do more with less and not being able to staff a class, the city of Fort Wayne?s fire department is now hiring again,? Fort Wayne Mayor Tom Henry announced Monday, surrounded at Station 1 by city firefighters and several City Council members.

Fire Chief Amy Biggs said the department?s goal is to hire 15 well-rounded, qualified firefighters from diverse cultural backgrounds.

?We want people who represent our community,? she said. ? ? The path is not easy, but the reward is gratifying.?

The fire department is currently staffed with 340 firefighters, Biggs said.

The 15 new candidates will bring the department closer to the 375 mark, the maximum number of firefighters the department is allowed to have, Biggs said.

The last time the Fort Wayne Fire Department hired a new class of firefighters was in 2008.

In recent years, the fire department has reduced the number of fire investigators from seven to five, building inspectors from 10 to 7, and public education officials from three to two, Biggs said earlier this year.

In doing so, the department has increased the workload for others in those positions and has had to sacrifice some of the programs related to fire prevention and awareness.

The hiring of new firefighters begins with an application process that began Monday and will continue through July 26.

The applicants will then be given a written exam and an orientation for the candidate physical ability test, or CPAT. Candidates will have up to eight weeks to prepare for the CPAT.

After the orientation, candidates will perform the CPAT, a panel interview, background investigation, fire chief interview and state agility testing including tests for acrophobia and claustrophobia.

If candidates remain eligible, they will then undergo a psychological and medical exam and seek approval from the pension board and merit commission before being appointed to the 17-week firefighter academy.

The entire process is expected to take between nine and 10 months, with a graduation date of May 2014, Biggs said.

A new local option income tax approved in June by the Fort Wayne City Council will pay for most of the $1.2 million needed for a class of 15 firefighters, she said.

The $1.2 million includes funding for the academy class, administrators for exams and other components of the hiring process ? as well as money to pay current firefighters overtime until the seats are filled, Biggs said.

Marty Bender, a city councilman and deputy police chief, said the council spent more than a year examining the city?s finances to find the best way to provide the funding the fire department needed for a new class.

?That?s where we came up with the idea to use the (local option income tax) that the state legislature made available to us,? he said.

?Some of the other ideas that were put forth would have got us to about the same spot, but they wouldn?t have been sustainable.

?In about two or three years, we would have to go through this again and figure out where ? we were going to get that money.?

jcrothers@jg.net

Source: http://www.journalgazette.net/article/20130709/LOCAL07/307099969/-1/LOCAL11

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